Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling.

Authors :: Williams, Anwen
Wang, Eddie C. Y.
Thurner, Lorenz
Liu, Chuan‐ju
Source :: Arthritis & Rheumatology; Dec2016, Vol. 68 Issue 12, p2845-2856, 12p
Publication Year :: 2016
Abstract: The article discusses tumor necrosis factor receptor (TNFR), death receptor 3 (DR-3), and progranulin (PGRN) pathways in bone remodeling and arthritis. Topics include interactions between PGRN and TNFR in bone remodeling and arthritis, cellular expression of death domain with tumor necrosis factor receptor superfamily (TNFRSF) members, and interactions between DR-3 and tumor necrosis factor-like molecule 1A (TL1A) in bone remodeling and arthritis.

Subjects :: BONE remodeling
ARTHRITIS
AUTOANTIBODIES
BONES
CELL receptors
CELLULAR signal transduction
GENE expression
GROWTH factors
GENETIC mutation
OSTEOARTHRITIS
RHEUMATOID arthritis
SPONDYLOARTHROPATHIES
TUMOR necrosis factors

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