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Cost and clinical outcome of islet transplantation in Norway 2010-2015.
- Source :
- Clinical Transplantation; Jan2017, Vol. 31 Issue 1, pn/a-N.PAG, 8p
- Publication Year :
- 2017
-
Abstract
- Islet transplantation is a minimally invasive β-cell replacement strategy. Islet transplantation is a reimbursed treatment in Norway. Here, we summarize the cost and clinical outcome of 31 islet transplantations performed at Oslo University Hospital ( OUS) from January 2010 to June 2015. Patients were retrospectively divided into three groups. Thirteen patients received either one or two islet transplantation alone ( ITA), while five patients received islet transplantation after previous solid organ transplantation. For the group receiving 2 ITA, Kaplan-Meier estimates show an insulin independence of 20% more than 4 years after their last transplantation. An estimated 70% maintain at least partial graft function, defined as fasting C-peptide >0.1 nmol L<superscript>−1</superscript>, and 47% maintain a HbA1c below 6.5% or 2 percent points lower than before ITA. For all groups combined, we estimate that 44% of the patients have a 50% reduction in insulin requirement 4 years after the initial islet transplantation. The average cost for an islet transplantation procedure was 347 297±60 588 NOK, or 35 424±6182 EUR, of which isolation expenses represent 34%. We hereby add to the common pool of growing experience with islet transplantation and also describe the cost of the treatment at our center. [ABSTRACT FROM AUTHOR]
- Subjects :
- CELL transplantation
KAPLAN-Meier estimator
INSULIN
MEDICAL care costs
Subjects
Details
- Language :
- English
- ISSN :
- 09020063
- Volume :
- 31
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Clinical Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 120550844
- Full Text :
- https://doi.org/10.1111/ctr.12871