Longitudinal evaluation of cerebral white matter hyperintensities lesion volume in children with sickle cell disease.

The article presents a research on longitudinal evaluation of cerebral white matter hyperintensities (WMH) lesion volume in children with sickle cell disease (SCD). Topics discussed include magnetic resonance imaging (MRI) as a part of SCD clinical care; measuring of white matter lesion volume by drawing all lesions on each fluid attenuation inversion recovery (FLAIR) image; and lesion volume was increased in some patients and it remained the same in other patients.