Detection of SERPINB7 mutation can distinguish Nagashima-type palmoplantar keratoderma from other keratodermas with palmoplantar lesions.

Authors :: Hashimoto, T.
Teye, K.
Numata, S.
Suga, Y.
Hamada, T.
Ishii, N.
Source :: Clinical & Experimental Dermatology; Apr2017, Vol. 42 Issue 3, p342-345, 4p
Publication Year :: 2017
Abstract: The article discusses a study concerning the essential of screening for serpin peptidase inhibitor (SERPINB7) mutations to differentiate PPKN from PPK and non-PPK keratinizing diseases with paloplantar skin lesions. Identification of responsible genes for SERPINB7, is also emphasized. Also mentioned is the genetic study of SERPINB7 in patients with various diseases.

Subjects :: SERINE proteinase inhibitors
PEPTIDASE genetics
PEPTIDASE
ETIOLOGY of diseases
TRANSPEPTIDATION

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