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Calmodulin and PI(3,4,5)P3 cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.

Authors :
Xinxin Wang
Boyken, Scott E.
Jiancheng Hu
Xiaolu Xu
Rimer, Ryan P.
Shea, Madeline A.
Shaw, Andrey S.
Andreotti, Amy H.
Yina H. Huang
Source :
Science Signaling; 8/5/2014, Vol. 7 Issue 337, p1-12, 12p
Publication Year :
2014

Details

Language :
English
ISSN :
19450877
Volume :
7
Issue :
337
Database :
Complementary Index
Journal :
Science Signaling
Publication Type :
Academic Journal
Accession number :
122121912
Full Text :
https://doi.org/10.1126/scisignal.2005147