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Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s disease.
- Source :
- Science Translational Medicine; 10/12/2016, Vol. 8 Issue 360, p1-10, 10p, 2 Charts, 5 Graphs
- Publication Year :
- 2016
-
Abstract
- The article presents a study which examined the pharmacokinetics and pharmacodynamics of CVT-301, an inhalation powder formulation of levodopa, as treatment of OFF episodes in patients with Parkinson's disease (PD). Also cited are the effects of CVT-301 in dogs, cough as the most common adverse event during preclinical trials, and the rapid absorption of inhaled CVT-301 in humans.
Details
- Language :
- English
- ISSN :
- 19466234
- Volume :
- 8
- Issue :
- 360
- Database :
- Complementary Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 122146272
- Full Text :
- https://doi.org/10.1126/scitranslmed.aad8858