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Controllable n-Fe2O3@graphene nanomaterials by ALD applied in an aptasensor with enhanced electrochemical performance for thrombin detection.
- Source :
- Dalton Transactions: An International Journal of Inorganic Chemistry; 6/21/2017, Vol. 46 Issue 23, p7434-7440, 7p
- Publication Year :
- 2017
-
Abstract
- An elegant atomic layer deposition (ALD) method has been employed for the controllable preparation of a uniform Fe<subscript>2</subscript>O<subscript>3</subscript>-coated graphene nanostructure (Fe<subscript>2</subscript>O<subscript>3</subscript>@graphene). The Fe<subscript>2</subscript>O<subscript>3</subscript> coating thickness of the Fe<subscript>2</subscript>O<subscript>3</subscript>@graphene nanostructure can be tuned by varying the cycle number of Fe<subscript>2</subscript>O<subscript>3</subscript> ALD. The produced Fe<subscript>2</subscript>O<subscript>3</subscript>@graphene composites are characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy and cyclic voltammetry (CV). It is revealed that Fe<subscript>2</subscript>O<subscript>3</subscript> is effectively deposited on the surface of graphene. Combined with the high affinity and specificity of an aptamer, a simple, rapid and sensitive electrochemical aptasensor was successfully fabricated for thrombin detection. The resulting electrochemical aptasensor displays a linear response to thrombin in the 1.0 × 10<superscript>−11</superscript> to 4.0 × 10<superscript>−9</superscript> M concentration range with the detection limit of 1.0 × 10<superscript>−12</superscript> M (at an S/N of 3). The described controllable multifunctional graphene nanomaterials from ALD are expected to be applied in a biosensing platform which will exhibit wide applications in biological, medical, and environmental fields. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14779226
- Volume :
- 46
- Issue :
- 23
- Database :
- Complementary Index
- Journal :
- Dalton Transactions: An International Journal of Inorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 123581103
- Full Text :
- https://doi.org/10.1039/c7dt01184a