Antimicrobial and antioxidant activities of a new metabolite from Quercus incana.

Phytochemical investigations ofQuercus incanaled to the isolation of a new catechin derivative quercuschin (1), along with six known compounds: quercetin(2), methyl gallate (3), gallic acid (4), betulinic acid (5), (Z)-9-octadecenoic acid methyl ester (6) and β-sitosterol glucoside (7) from the ethyl acetate fraction of methanolic extract of the bark. Compound1was screened for its antibacterial, antifungal and antioxidant potential. Antibacterial and antifungal activities of the compound were tested against different bacterial and fungal strains, employing the agar well diffusion methods. The antibacterial activity was the highest againstStreptococcus pyogeneswith 80.0% inhibition, while the antifungal activity of the compound was the highest againstCandida glabratawith 80.5% inhibition. The results of the antioxidant activity indicated that the compound exhibited antioxidant activity comparable to that of standard, butylated hydroxyanisole (51.2 μg/10 μl versus 45.9 μg/10 μl). [ABSTRACT FROM PUBLISHER]