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A new indole alkaloid with anti-inflammatory activity from Nauclea officinalis.
- Source :
- Natural Product Research; Sep2017, Vol. 31 Issue 18, p2107-2112, 6p
- Publication Year :
- 2017
-
Abstract
- A new indole alkaloid, 17-O-methyl-19-(Z)-naucline (1), together with seven known alkaloids (2-8), were isolated from the stems and leaves of Nauclea officinalis. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons their data with those reported in the literature. 17-Omethyl-19-(Z)-naucline (1) showed significant inhibitory activity on nitric oxide production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells in vitro with an IC<subscript>50</subscript> value of 3.6 µM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 31
- Issue :
- 18
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 124633932
- Full Text :
- https://doi.org/10.1080/14786419.2016.1277351