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Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Ab and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.

Authors :
Kuruva, Chandra Sekhar
Manczak, Maria
Xiangling Yin
Ogunmokun, Gilbert
Reddy, Arubala P.
Reddy, P. Hemachandra
Source :
Human Molecular Genetics; 9/1/2017, Vol. 26 Issue 17, p3375-3395, 21p
Publication Year :
2017

Details

Language :
English
ISSN :
09646906
Volume :
26
Issue :
17
Database :
Complementary Index
Journal :
Human Molecular Genetics
Publication Type :
Academic Journal
Accession number :
124755574
Full Text :
https://doi.org/10.1093/hmg/ddx226