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ARTISAN PCR: rapid identification of full-length immunoglobulin rearrangements without primer binding bias.
- Source :
- British Journal of Haematology; Sep2017, Vol. 178 Issue 6, p983-986, 4p, 1 Diagram, 1 Graph
- Publication Year :
- 2017
-
Abstract
- The article focuses on a study regarding the use of polymerase chain reaction (PCR) for rapid identification of full-length immunoglobulin rearrangements without primer binding bias. It mentions that B cells recognize specific antigens by their membrane-bound B-cell receptor (BCR). It also mentions that non-templated point mutations are introduced into BCR genes by somatic hypermutation (SHM).
- Subjects :
- POLYMERASE chain reaction
IMMUNOGLOBULINS
B cells
ANTIGENS
GENETIC mutation
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 178
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 125070475
- Full Text :
- https://doi.org/10.1111/bjh.14180