Back to Search
Start Over
Motivational wheel running reverses cueing behavioural inflexibility in rodents.
- Source :
- Journal of Neural Transmission; Dec2017, Vol. 124 Issue 12, p1635-1640, 6p
- Publication Year :
- 2017
-
Abstract
- Behavioural inflexibility and associated atypical learning behaviours are common clinical manifestations of the autism spectrum disorder (ASD) phenotype. Despite advances in our understanding of ASD, little research has been devoted to experimental interventions that might help to circumvent behavioural inflexibility in ASD. The current paper suggests that motivational locomotion in the form of wheel running can reduce behavioural inflexibility and learning impairments in an ASD rat model, and discusses how the strategy of reward-coupled locomotor activity may lead to clinical interventions for children with ASD. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03009564
- Volume :
- 124
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Journal of Neural Transmission
- Publication Type :
- Academic Journal
- Accession number :
- 126215246
- Full Text :
- https://doi.org/10.1007/s00702-017-1790-z