A study of Salvia fruticosa Mill subsp. thomasii (Lacaita) Brullo, Guglielmo, Pavone & Terrasi, an endemic Sage of Southern Italy.

The aim of this study was to investigate the essential oil profile ofSalvia thomasii(Southern Italy) and to assess the relationship of this taxonomic unit toS. fruticosa. The essential oil, obtained by hydrodistillation, was analysed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The main components are β-pinene, viridiflorol, 1,8-cineole, camphor, α-pinene andtrans-caryophyllene. The oil was tested for its potential antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), Ferric Reducing Ability Power (FRAP) and β-carotene bleaching test. Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity assays were used to screen the neuroprotective effect of the essential oil. A clear distinction of the two taxonomic units emerge by the comparison ofS. thomasiiandS. fruticosas.l. essential oil composition. Considering the weak morphological differences and the clear-cut geographic separation we propose to treat the Italian unit at subspecies level asSalvia fruticosaMill subsp.thomasii(Lacaita) Brullo, Guglielmo, Pavone & Terrasi. [ABSTRACT FROM PUBLISHER]