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Visible light induced Trifluoromethyl Migration: Easy Access to α‐Trifluoromethylated Ketones from Enol Triflates.
- Source :
- Advanced Synthesis & Catalysis; 1/17/2018, Vol. 360 Issue 2, p267-271, 5p
- Publication Year :
- 2018
-
Abstract
- Abstract: Herein, we reported a novel method to synthesize α‐trifluoromethylated ketones from enol triflates. Involving a cascade sulfur dioxide extrusion and a CF<subscript>3</subscript> (trifluoromethyl) radical addition process, this reaction proceeds at room temperature and is driven by visible light irradiation. This protocol bears good functional group compatibility, which can generate the desired products in good to excellent yields even in gram scale. It is hoped that this approach to generate CF<subscript>3</subscript> radicals from enol triflates can be used in other radical‐involved reactions. [ABSTRACT FROM AUTHOR]
- Subjects :
- KETONURIA
KETOACIDOSIS
OXO compounds
VISIBLE spectra
REFRIGERANTS
Subjects
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 360
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 127390851
- Full Text :
- https://doi.org/10.1002/adsc.201701051