Coordination-driven self-assembly of a Pt(iv) prodrug-conjugated supramolecular hexagon.

This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines. [ABSTRACT FROM AUTHOR]