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Tonometer validation and intraocular pressure reference values in the normal chinchilla (<italic>Chinchilla lanigera)</italic>.
- Source :
- Veterinary Ophthalmology; Jan2018, Vol. 21 Issue 1, p4-9, 6p
- Publication Year :
- 2018
-
Abstract
- Abstract: Objectives: To determine accuracy and precision of three commonly used tonometers (TonoVet<superscript>®</superscript> and TonoLab<superscript>®</superscript> (ICare Oy, Finland)—rebound tonometers, and Tono‐Pen VET™ (Reichert, NY)—applanation tonometer) in normal chinchillas, and to establish a normal intraocular pressure (IOP) reference range in this species. Methods: The anterior chambers of three chinchilla eyes were cannulated <italic>ex vivo</italic> and readings obtained at manometric IOPs from 5 to 80 mmHg, using each of the three tonometers in random order. Data were analyzed by linear regression, ANOVA, and Bland–Altman plots. Tonometry was performed in both eyes of 60 chinchillas (age 8 weeks–16.2 years) using the TonoVet<superscript>®</superscript> and relationship between age and IOP analyzed using linear regression. For all statistical tests, <italic>P</italic> < 0.05 was significant. Results: Intraocular pressure values obtained using the Tono‐Pen VET™ and TonoVet<superscript>®</superscript> (in dog calibration mode;‘d’) showed strong linear correlation with manometry within the physiologic and clinically relevant range of IOP (0–50 mmHg). The TonoVet<superscript>®</superscript> ‘d’ setting displayed significantly greater precision over the full range of IOP evaluated than the Tono‐Pen VET™, and both TonoVet and Tono‐Pen VET™ were significantly more accurate than the TonoLab<superscript>®</superscript> tonometer. Mean ± SD IOP (TonoVet<superscript>®</superscript> ‘d’) in chinchillas was 9.7 ± 2.5 mmHg, and the 95% reference interval was 4.7–14.7 mmHg. Conclusions: Both the Tono‐Pen VET™ and TonoVet<superscript>®</superscript> provided clinically acceptable estimates of IOP in chinchillas. The TonoVet<superscript>®</superscript> provides accurate and precise IOP values, while Tono‐Pen VET™ derived measurements showed greater variability. Values obtained either with the TonoLab<superscript>®</superscript> or TonoVet<superscript>®</superscript> used in the ‘unspecified’ calibration setting were inaccurate in this species. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14635216
- Volume :
- 21
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Veterinary Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 127563937
- Full Text :
- https://doi.org/10.1111/vop.12468