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Effects of Laparoscopic Roux-en-Y Gastric Bypass on Chinese Type 2 Diabetes Mellitus Patients with Different Levels of Obesity: Outcomes After 3 Years’ Follow-Up.
- Source :
- Obesity Surgery; Mar2018, Vol. 28 Issue 3, p702-711, 10p
- Publication Year :
- 2018
-
Abstract
- Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) has been proven to be effective on treating type 2 diabetes mellitus (T2DM) in severely obese patients, but whether LRYGB surgery should be performed in obese class I patients is controversial.Materials and Methods: A retrospective study of 3-year bariatric and metabolic outcomes in different obese class T2DM patients who underwent LRYGB was conducted to compare the effectiveness of LRYGB in obese class I patients with that in obese class II/III patients in a Chinese T2DM population.Results: Totally, 58 patients with class I obesity and 45 patients with class II/III obesity were enrolled in this study. Major complications included two cases of incomplete intestinal obstructions and one anastomotic leak. The remission rates of T2DM were 70.6% in obese class I group and 77.8% in obese class II/III group at 1 year after surgery and 55.6 versus 64.3% at 3 years (all <italic>P</italic> > 0.05). Logistic regression analysis showed that higher waist circumference, lower fasting plasma glucose, and higher FCP at 2 h of OGTT were independently associated with diabetes remission at 1 year after surgery. At 1 year and thereafter, the percentage of excess weight loss was significantly greater in obese class II/III patients. At 3 years, body mass index was not significantly different between the two groups, and the obese class I patients had high recurrence rates of hypertension and hyperuricemia.Conclusions: LRYGB surgery is feasible, safe, and effective in Chinese obese class I patients with T2DM. [ABSTRACT FROM AUTHOR]
- Subjects :
- BARIATRIC surgery
LAPAROSCOPY
PEOPLE with diabetes
BODY mass index
GASTRIC bypass
Subjects
Details
- Language :
- English
- ISSN :
- 09608923
- Volume :
- 28
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Obesity Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 127876924
- Full Text :
- https://doi.org/10.1007/s11695-017-2903-3