Back to Search
Start Over
Inherited forms of bladder cancer: a review of Lynch syndrome and other inherited conditions.
- Source :
- Future Oncology; Feb2018, Vol. 14 Issue 3, p277-290, 14p
- Publication Year :
- 2018
-
Abstract
- Environmental factors that play a role in the urothelial carcinogenesis have been well characterized. Current research is continuously exploring potential heritable forms of bladder cancer. Lynch syndrome is a well-known inheritable disease that increases the risk for a variety of cancers, including urothelial carcinomas. Screening of patients with known Lynch syndrome is important to evaluate for development of new primary tumors. Further study may provide more information on what level of follow-up each patient needs. Recent data suggest that mismatch repair mutations confer a greater risk for urothelial cancer. Additional large patient series as well as advancement of molecular testing may provide triage for Lynch syndrome patients in regards to the frequency and type of screening best suited for individual patient. [ABSTRACT FROM AUTHOR]
- Subjects :
- GENETIC disorder diagnosis
DIAGNOSIS of hereditary nonpolyposis colorectal cancer
BLADDER tumors
DEGENERATION (Pathology)
DISEASE susceptibility
GENETIC disorders
GENETIC techniques
MEDICAL screening
PROGNOSIS
PUBLIC health surveillance
HEREDITARY nonpolyposis colorectal cancer
EARLY detection of cancer
HEREDITARY cancer syndromes
DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 14796694
- Volume :
- 14
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Future Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 128021950
- Full Text :
- https://doi.org/10.2217/fon-2017-0346