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The Minneapolis-Manchester Quality of Life Instrument: reliability and validity of the Adult Form in cancer survivors.
- Source :
- Quality of Life Research; Feb2018, Vol. 27 Issue 2, p321-332, 12p, 6 Charts
- Publication Year :
- 2018
-
Abstract
- <bold>Purpose: </bold>Childhood cancer survivors are at risk for deficits in health-related quality of life (HRQL) as they age. Youth (8-12 years) and adolescent (13-20 years) versions of the Minneapolis-Manchester Quality of Life Instrument (MMQL) have been developed to address survivor-specific issues and are currently in use; the MMQL-Adult Form has now been developed to assess HRQL in childhood cancer survivors aged 21-55 years.<bold>Methods: </bold>The MMQL-Adult Form was administered to 499 adults: 65 cancer patients on-therapy, 107 off-therapy, and 327 healthy controls. Forty-four percent of patients were under 30 years old at cancer diagnosis. Principal components analysis was performed. We evaluated internal consistency reliability, stability (re-administration of the MMQL-Adult Form 2 weeks later), construct validity (concurrent administration of the SF-36), and known-groups validity (score comparisons across the three groups).<bold>Results: </bold>Principal components analysis resulted in retention of 44 items across six scales: social functioning, physical functioning, cognitive functioning, outlook on life, body image, and psychological functioning. Internal consistency (Cronbach's α) was 0.80-0.90 for individual scales and 0.95 overall. Strong intraclass correlations (0.98 overall) indicated high stability. The MMQL-Adult Form distinguished between known groups; healthy controls scored better than patients on four of six scales. The MMQL-Adult Form scales correlated highly with similar SF-36 scales, demonstrating construct validity.<bold>Conclusions: </bold>The MMQL-Adult Form is a reliable and valid self-report instrument for measuring multidimensional HRQL in cancer survivors. Development of this instrument ensures availability of a tool enabling cross-sectional and longitudinal assessment of HRQL in childhood cancer survivors as they age. [ABSTRACT FROM AUTHOR]
- Subjects :
- QUALITY of life
CANCER patients
CHILDHOOD cancer
CANCER treatment
PRINCIPAL components analysis
EXPERIMENTAL design
FACTOR analysis
RESEARCH methodology
PSYCHOMETRICS
QUESTIONNAIRES
RESEARCH evaluation
STATISTICAL reliability
MULTITRAIT multimethod techniques
RESEARCH methodology evaluation
DATA analysis software
Subjects
Details
- Language :
- English
- ISSN :
- 09629343
- Volume :
- 27
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Quality of Life Research
- Publication Type :
- Academic Journal
- Accession number :
- 128149481
- Full Text :
- https://doi.org/10.1007/s11136-017-1671-9