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You have free access to this contentCD274 (PD-L1)/PDCD1 (PD-1) expression in de novo and transformed diffuse large B-cell lymphoma.

Authors :
Kwiecinska, Anna
Tsesmetzis, Nikolaos
Ghaderi, Mehran
Kis, Lorand
Saft, Leonie
Rassidakis, George Z.
Source :
British Journal of Haematology; Mar2018, Vol. 180 Issue 5, p744-748, 5p
Publication Year :
2018

Abstract

The article focuses on factors of the tumour microenvironment are associated with patient survival and time to transformation in follicular lymphoma (FL). It mentions impact of PDCD1 (PD-1)-positive tumour infiltrating T-lymphocytes (TILs) and CD274 (PD-L1)-positive macrophages and single antibody for CD274. It also mentions immunohistochemical detection of CD274 in macrophages or the lymphoma cells and paraffin-embedded (FFPE) tissues.

Details

Language :
English
ISSN :
00071048
Volume :
180
Issue :
5
Database :
Complementary Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
128179294
Full Text :
https://doi.org/10.1111/bjh.14432