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Lipids at the crossroad: Shaping biological membranes heterogeneity defines trafficking pathways.
- Source :
- PLoS Biology; 2/26/2018, Vol. 16 Issue 2, p1-7, 7p, 1 Diagram
- Publication Year :
- 2018
-
Abstract
- Lipids are essential components of biological membranes that present a wide diversity in eukaryotic cells. Recent impressive advances in lipid biochemistry and biophysics have enabled a refocus of our view of lipids as functional units for cellular activity. However, the gap between molecular and cellular processes remains to be bridged. Here, 2 papers meet the burden of proof that choline transporters participate in local lipid composition modifications at the trans-Golgi network, an intracellular compartment that serves as the main sorting station in the cell. Localization of choline transporters to this precise compartment could be a way for plant cells to quickly modify the membrane lipid composition and asymmetry during both the allocation of cargos and the recruitment of trafficking machineries into distinct subcellular pathways. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15449173
- Volume :
- 16
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- PLoS Biology
- Publication Type :
- Academic Journal
- Accession number :
- 128188356
- Full Text :
- https://doi.org/10.1371/journal.pbio.2005188