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VHH Antibodies: Reagents for Mycotoxin Detection in Food Products.
- Source :
- Sensors (14248220); Feb2018, Vol. 18 Issue 2, p485, 13p, 1 Color Photograph, 4 Diagrams, 1 Chart
- Publication Year :
- 2018
-
Abstract
- Mycotoxins are the toxic secondary metabolites produced by fungi and they are a worldwide public health concern. A VHH antibody (or nanobody) is the smallest antigen binding entity and is produced by heavy chain only antibodies. Compared with conventional antibodies, VHH antibodies overcome many pitfalls typically encountered in clinical therapeutics and immunodiagnostics. Likewise, VHH antibodies are particularly useful for monitoring mycotoxins in food and feedstuffs, as they are easily genetic engineered and have superior stability. In this review, we summarize the efforts to produce anti-mycotoxins VHH antibodies and associated assays, presenting VHH as a potential tool in mycotoxin analysis. [ABSTRACT FROM AUTHOR]
- Subjects :
- FOOD microbiology
MYCOTOXINS
METABOLITES
PUBLIC health
IMMUNOGLOBULINS
IMMUNOASSAY
Subjects
Details
- Language :
- English
- ISSN :
- 14248220
- Volume :
- 18
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Sensors (14248220)
- Publication Type :
- Academic Journal
- Accession number :
- 128281678
- Full Text :
- https://doi.org/10.3390/s18020485