Back to Search
Start Over
Probing Substrate Diffusion in Interstitial MOF Chemistry with Kinetic Isotope Effects.
- Source :
- Angewandte Chemie International Edition; 3/26/2018, Vol. 57 Issue 14, p3676-3681, 6p
- Publication Year :
- 2018
-
Abstract
- Abstract: Metal–organic frameworks (MOFs) have garnered substantial interest as platforms for site‐isolated catalysis. Efficient diffusion of small‐molecule substrates to interstitial lattice‐confined catalyst sites is critical to leveraging unique opportunities of these materials as catalysts. Understanding the rates of substrate diffusion in MOFs is challenging, and few in situ chemical tools are available to evaluate substrate diffusion during interstitial MOF chemistry. Herein, we demonstrate nitrogen atom transfer (NAT) from a lattice‐confined Ru<subscript>2</subscript> nitride to toluene to generate benzylamine. We use the comparison of the intramolecular deuterium kinetic isotope effect (KIE), determined for amination of a partially deuterated substrate, with the intermolecular KIE, determined by competitive amination of a mixture of perdeuterated and undeuterated substrates, to establish the relative rates of substrate diffusion and interstitial chemistry. We anticipate that the developed KIE‐based experiments will contribute to the development of porous materials for group‐transfer catalysis. [ABSTRACT FROM AUTHOR]
- Subjects :
- METAL-organic frameworks
ISOTOPES
NITROGEN
AMINATION
POROUS materials
Subjects
Details
- Language :
- English
- ISSN :
- 14337851
- Volume :
- 57
- Issue :
- 14
- Database :
- Complementary Index
- Journal :
- Angewandte Chemie International Edition
- Publication Type :
- Academic Journal
- Accession number :
- 128708466
- Full Text :
- https://doi.org/10.1002/anie.201713244