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Axial modification inhibited H-aggregation of phthalocyanines in polymeric micelles for enhanced PDT efficacy.
- Source :
- Chemical Communications; 4/18/2018, Vol. 54 Issue 32, p3985-3988, 4p
- Publication Year :
- 2018
-
Abstract
- Axial modified phthalocyanine (BtPc), aiming at avoiding H-aggregation and utilizing long wavelength light, was designed and synthesized. With the aid of polymer nanotechnology, BtPc loaded polymeric micelles with strong singlet oxygen generating ability and enhanced photodynamic therapy efficiency were developed. Optical characterizations and in vitro evaluations proved that the BtPc loaded polymeric micelles hold great potential for photodynamic therapy. [ABSTRACT FROM AUTHOR]
- Subjects :
- PHTHALOCYANINES
MICELLES
PHOTODYNAMIC therapy
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 54
- Issue :
- 32
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 129136031
- Full Text :
- https://doi.org/10.1039/c7cc09954a