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Synthesis and biological activity of arylaliphatic <italic>N</italic>-(2-aminoethyl)-<italic>N</italic>-(2-hydroxy-2-phenylethyl)carboxamides.
- Source :
- Russian Chemical Bulletin; Jan2018, Vol. 67 Issue 1, p131-136, 6p
- Publication Year :
- 2018
-
Abstract
- <italic>N</italic>-(2-Aminoethyl)-<italic>N</italic>-(2-hydroxy-2-phenylethyl)carboxamides were synthesized from styrene oxide by ring opening with <italic>N</italic>,<italic>N</italic>-disubstituted ethylenediamines followed by <italic>N</italic>-acylation. Synthesized compounds have pronounced antiarrhythmic activity and low toxicity. [ABSTRACT FROM AUTHOR]
- Subjects :
- STYRENE oxide
ETHYLENEDIAMINE
ACYLATION kinetics
ARRHYTHMIA diagnosis
CARBOXAMIDES
Subjects
Details
- Language :
- English
- ISSN :
- 10665285
- Volume :
- 67
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Russian Chemical Bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 129180296
- Full Text :
- https://doi.org/10.1007/s11172-018-2048-0