Heavy/light chain ratio for the assessment of minimal residual disease in myeloma patients achieving complete response.

The article discusses findings of a study on use of heavy/light chain (HCL) ratio for the assessment of minimal residual disease in myeloma patients achieving complete response. It states that a study of HLC ratio, and its comparison with free light chain (FLC) ratio, for the evaluation of minimal residual disease (MRD) and early detection of relapse, and mentions that Abnormal HLC ratios at presentation have been associated with shorter overall survival in multiple myeloma.