A literature-based phytochemical evidence and biological activities of Trichosanthes dioica Roxb.

A review is done on the phytochemical profile and biological effects of Trichosanthes dioica Roxb. The findings suggest that this herb contains a number of important phytochemicals, which may link with its promising pharmacological activities such as antioxidant, anti-inflammatory, antimicorbial, anthelmintic, burn/wound healing, anti-cancer, anti-ulcer, anti-hypertensive, anti-diabetic, lipid lowering, neurological (anti-neuroinflammatory, anti-nociceptive and analgesic), gastro-protective, hepatoprotective, nephroprotective, cardio-protective, immunomodulatory, hair growth facilitatory and so on. With these, the clinical trial reports suggest that this herb can be used in the treatment of duodenal ulcer and skin disorder. Extracts from various parts of this herb and its derived compounds can be used to treat above-mentioned diseases/purposes, especially oxidative stress and its related diseases. More researches are highly appreciated to isolate and identify the active principles and their mechanisms of action of the biological activities. [ABSTRACT FROM AUTHOR]