Lysosome-targeting ratiometric fluorescent pH probes based on long-wavelength BODIPY.

Authors :: Zhu, Mengliang
Xing, Peipei
Zhou, Yabin
Gong, Lei
Zhang, Jinghui
Qi, Dongdong
Bian, Yongzhong
Du, Hongwu
Jiang, Jianzhuang
Source :: Journal of Materials Chemistry B; 7/21/2018, Vol. 6 Issue 27, p4422-4426, 5p
Publication Year :: 2018
Abstract: BODIPY-based probes were developed for the ratiometric fluorescence detection of pH values. They showed high sensitivity under acidic conditions via a protonation-modulated ICT mechanism and could selectively stain lysosomes, and thus could be applied for imaging and detecting abnormal pH decreases in live cells. [ABSTRACT FROM AUTHOR]

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