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Lipolytic effect of compounds isolated from leaves of mulberry (Morus alba L.) in 3T3-L1 adipocytes.
- Source :
- Natural Product Research; Aug2018, Vol. 32 Issue 16, p1963-1966, 4p
- Publication Year :
- 2018
-
Abstract
- In this study, 19 known compounds were isolated from mulberry (Morus alba L.) leaves. The lipid accumulation inhibitory activity of the isolated compounds was investigated. Compounds 4 and 12 showed good anti-adipogenic activity based on 3T3-L1 adipocytes with values of 36.6 ± 9.0 and 34.7 ± 4.0%, respectively. In addition, compounds 3, 6 and 15 showed significant inhibitory activity with values from 15.4 to 21.2% and compounds 2, 8-9 and 17-18 exhibited weak activity with values ranging from 2.1 to 10.7% at a concentration of 40.0 μM. These results show the potentiality that mulberry leaf is an excellent inhibitory phytochemical source against lipid accumulation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 32
- Issue :
- 16
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 131011183
- Full Text :
- https://doi.org/10.1080/14786419.2017.1354190