Back to Search
Start Over
Oxygen Consumption during Histamine Release by Antigen and Compound 48/80.
- Source :
- Immunology; May65, Vol. 8 Issue 5, p511-518, 8p
- Publication Year :
- 1965
-
Abstract
- The oxygen consumption of isolated rat mast cells has been determined using a micro capillary, respirometer designed by Cunningham and Kirk and modified to permit stirring and addition of reactants. Uptake ranged from 0·5 pl. per cell per minute in 100 per cent O<subscript>2</subscript> to 0·1 pl. per cell per minute in 1 per cent O<subscript>2</subscript>. It remained steady for at least 1 hour and was not affected by the presence of glucose. Under a variety of conditions neither histamine release by antigen added to sensitized cells nor by compound 48/80 added to normal cells resulted in any increase in the rate of oxygen uptake. Oxygen does not appear to be a rate limiting factor. [ABSTRACT FROM AUTHOR]
- Subjects :
- MAST cells
RESPIRATORY measurements
HISTAMINE
ANTIGENS
ANAPHYLAXIS
IMMUNOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 8
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13277642