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Idelalisib rapidly improves platelet function tests in patients with chronic lymphocytic leukaemia.

Authors :
Reda, Gianluigi
Cassin, Ramona
Artoni, Andrea
Fattizzo, Bruno
Lecchi, Anna
La Marca, Silvia
Bucciarelli, Paolo
Levati, Giorgia V.
Peyvandi, Flora
Cortelezzi, Agostino
Source :
British Journal of Haematology; Dec2018, Vol. 183 Issue 5, p825-828, 4p, 1 Chart, 1 Graph
Publication Year :
2018

Abstract

The article presents a study which examined the influence of idelalisib on platelet aggregation and coagulation tests in patients with chronic lymphocytic leukaemia (CLL). In the study, the subjects took either ibrutinib or idelalisib based on their baseline characteristics, drug interactions, and side effects. Also cited is the use of the validated questionnaire for bleeding diathesis, the International Society on Thrombosis and Haemostasis bleeding assessment tool (ISTH BAT), in the study.

Details

Language :
English
ISSN :
00071048
Volume :
183
Issue :
5
Database :
Complementary Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
133260454
Full Text :
https://doi.org/10.1111/bjh.15052