Back to Search
Start Over
Primary and Secondary Immune Responses of the Marine Toad (<em>Bufo marinus</em>) to Bacteriophage f2.
- Source :
- Immunology; Mar71, Vol. 20 Issue 3, p373-380, 8p
- Publication Year :
- 1971
-
Abstract
- The primary and secondary immune responses of toads (Bufo marinus) were studied using the bacteriophage f2 as antigen. Antibodies were identified in the serum 2 weeks after primary immunization and peak antibody levels were reached at 6 weeks. Although both IgM and IgG antibodies can be found in toad serum, most of the antibody activity in our animals persisted in the IgM fraction until 8 weeks after immunization. When a second injection of antigen was given 4 weeks after primary immunization, there was a marked increase in the total serum antibody activity and IgG antibodies were found as early as 4 weeks after the second injection of antigen. These observations suggest that the toad, B. marinus, is capable of a true secondary response to the bacteriophage f2. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNE response
RHINELLA marina
BACTERIOPHAGES
ANTIGENS
IMMUNOGLOBULINS
IMMUNIZATION
Subjects
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 20
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13362340