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The Demonstration of the Involvement of Antibody in the <em>in vitro</em> Lysis of Chicken Erythrocytes by Allergized Spleen Cells.
- Source :
- Immunology; Dec74, Vol. 27 Issue 6, p1053-1062, 10p
- Publication Year :
- 1974
-
Abstract
- The experiments described demonstrate that the in vitro lysis of chicken erythrocytes (CRC) by allergized mouse spleen cells (ASC) is an antibody-dependent phenomenon. Supernatants obtained from cultures of ASC were shown to contain antibody which could effect antibody-dependent cell-mediated cytotoxicity. The cytolysis observed with ASC was inhibited by both an IgG fraction and a F(ab')<subscript>2</subscript> portion of rabbit anti-mouse IgG. No inhibition was obtained by pretreating the ASC with AKR anti-C3Hθ serum and guinea-pig complement. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 27
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13370157