Selective Separation of Isomeric Dicarboxylic Acid by the Preferable Crystallization of Metal‐Organic Frameworks.

Simple and effective separation of isomeric organic molecules is an important but challenging task. Herein, we successfully developed a selective crystallization strategy to separate the mixtures of isomeric dicarboxylic acids (DCAs) for the first time. The target DCAs could be preferably combined with crystallization inducer of Zr4+ ions to form a pre‐designed metal‐organic frameworks (MOFs) crystal structure whereas the entry of non‐target isomeric DACs into the MOFs lattice could be exclusively inhibited. Several isomeric pairs were exemplified to verify the extensibility and validity of the developed strategy. iSelect! An extensible strategy has been proposed to separate the mixtures of isomeric dicarboxylic acids by selectively crystallizing the target isomers into a pre‐designed MOFs crystal. [ABSTRACT FROM AUTHOR]