Back to Search
Start Over
The role of the major histocompatibility complex in <em>in vitro</em> antibody responses; MHC restriction in responses involving linked recognition of antigenic determinants is not solely consequent to T cell-accessory cell restrictions.
- Source :
- Immunology; Feb84, Vol. 51 Issue 2, p351-360, 10p
- Publication Year :
- 1984
-
Abstract
- Major histocompatibility complex (MHC) restrictions in the secondary antibody response in vitro to the soluble protein antigen trinitrophenyl keyhole limpet haemocyanin (TNP-KLH) were investigated in this study. Experimental conditions were employed which ensured that co-operation between KLH-primed T cells and TNP-primed B cells was possible only through linked recognition of carrier and haptenic determinants. Under such conditions co-operation between T and B cells appears to be MHC-restricted.
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 51
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13397934