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Determining predictors of sepsis at triage among children under 5 years of age in resource-limited settings: A modified Delphi process.
- Source :
- PLoS ONE; 1/28/2019, Vol. 14 Issue 1, p1-14, 14p
- Publication Year :
- 2019
-
Abstract
- Sepsis is a life-threatening dysfunction of the immune system leading to multiorgan failure that is precipitated by infectious diseases and is a leading cause of death in children under 5 years of age. It is necessary to be able to identify a sick child at risk of developing sepsis at the earliest point of presentation to a healthcare facility so that appropriate care can be provided as soon as possible. Our study objective was to generate a list of consensus-driven predictor variables for the derivation of a prediction model that will be incorporated into a mobile device and operated by low-skilled healthcare workers at triage. By conducting a systematic literature review and examination of global guideline documents, a list of 72 initial candidate predictor variables was generated. A two-round modified Delphi process involving 26 experts from both resource-rich and resource-limited settings, who were also encouraged to suggest new variables, yielded a final list of 45 predictor variables after evaluating each variable based on three domains: predictive potential, measurement reliability, and level of training and resources required. The final list of predictor variables will be used to collect data and contribute to the derivation of a prediction model. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNE system
MEDICAL personnel
DELPHI method
SEPSIS
ACQUISITION of data
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 14
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- PLoS ONE
- Publication Type :
- Academic Journal
- Accession number :
- 134315631
- Full Text :
- https://doi.org/10.1371/journal.pone.0211274