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Three-dimensional porous Cu@Cu2O aerogels for direct voltammetric sensing of glucose.
- Source :
- Microchimica Acta; Mar2019, Vol. 186 Issue 3, p1-1, 1p
- Publication Year :
- 2019
-
Abstract
- Three-dimensional Cu@Cu<subscript>2</subscript>O aerogels with excellent electrocatalytic activity were prepared and used as electrode matrix for constructing novel electrochemical glucose sensors. The aerogels were obtained by adding a fresh solution of NaBH<subscript>4</subscript> into a mixture of CuCl<subscript>2</subscript> and NaOH aqueous solutions under stirring at room temperature. The aerogels were assembled with Cu or Cu<subscript>2</subscript>O nanoparticles. The materials show superfine spongy-like structures with large surface-to-volume ratio, numerous active sites and good solubility. The Cu@Cu<subscript>2</subscript>O aerogels show highly efficient electrochemical activity toward glucose oxidation with a relatively low-onset potential (0.25 V) in 0.1 M NaOH solution. This non-enzymatic glucose sensor offers a low detection limit of 0.6 μM (S/N = 3), a high sensitivity (195 mA M<superscript>−1</superscript> cm<superscript>−2</superscript>), and two wide linear ranges (0.001-5.2 mM, 5.2-17.1 mM) at a working voltage of 0.6 V (vs. Ag/AgCl) in alkaline solution. While in neutral pH values, the respective data are a linear analytical range from 0.1 to 10 mM; a detection limit of 54 μM (S/N = 3) and a sensitivity of 12 mA M<superscript>−1</superscript> cm<superscript>−2</superscript> at scan rate of 100 mV s<superscript>−1</superscript>. The sensor possesses high selectivity, good reproducibility and long-time stability. It was utilized to determine glucose levels in (spiked) human serum samples, and satisfactory results were obtained.Schematic presentation of a glassy carbon electrode modified with 3D porous Cu@Cu<subscript>2</subscript>O aerogels. The aerogels were obtained by a reduction reaction at room temperature (Scheme 1A). The aerogel networks were used to develop a highly sensitive electrochemical sensing platform for the detection of glucose (Scheme 1B). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00263672
- Volume :
- 186
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Microchimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 135450838
- Full Text :
- https://doi.org/10.1007/s00604-019-3263-6