Reduced regulatory T cells (Treg) in bone marrow preferentially associate with the expansion of cytotoxic T lymphocytes in low risk MDS patients.

The article offers information on reducing regulatory T cells in bone marrow preferentially associate with the expansion of cytotoxicT lymphocytes in low risk myelodysplastic syndromes (MDS) patients; and mentions the myelodysplastic syndromes (MDS) include clonal bone marrow (BM) disorders characterised by the emergence of dysplastic progenitors in the context of ineffective haematopoiesis, peripheral cytopenias and increased risk of acute myeloid leukaemia (AML).