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Phase II trial to investigate efficacy and safety of bendamustine, dexamethasone and thalidomide in relapsed or refractory multiple myeloma patients after treatment with lenalidomide and bortezomib.

Authors :
Mian, Michael
Pescosta, Norbert
Badiali, Stefania
Cappelletto, Paola Cristina
Marcheselli, Luigi
Luminari, Stefano
Patriarca, Francesca
Zambello, Renato
Pascarella, Anna
Tagariello, Giuseppe
Marabese, Alessandra
Mondello, Patrizia
Billio, Atto
Cortelazzo, Sergio
Source :
British Journal of Haematology; Jun2019, Vol. 185 Issue 5, p944-947, 4p, 1 Diagram, 2 Charts
Publication Year :
2019

Abstract

The article focuses on a research which aims to evaluate the efficacy of bendamustine, dexamethasone and thalidomide in relapsed or refractory multiple myeloma patients following lenalidomide and bortezomib therapy or who were ineligible to receive such drugs as measured by the rate of response in terms of overall response rate. It also aims to assess the tolerability and toxicity and evaluate the time to treatment failure, overall survival, and disease-free survival.

Details

Language :
English
ISSN :
00071048
Volume :
185
Issue :
5
Database :
Complementary Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
136661951
Full Text :
https://doi.org/10.1111/bjh.15645