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Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization.

Authors :
Salinas, Linda J.
Fares, Elias
Drevets, Douglas A.
McCloskey, Cindy B.
Gutierrez, Andres
Princiotta, Michael
Source :
Infection; Jun2019, Vol. 47 Issue 3, p489-492, 4p
Publication Year :
2019

Abstract

Background: Listeria monocytogenes is a food-borne, facultative intracellular bacterium that causes severe diseases such as sepsis and meningoencephalitis in immunocompromised hosts. Because it stimulates robust T-lymphocyte-mediated responses, attenuated L. monocytogenes are candidate vaccine vectors for tumor immunotherapy. Case: We report a case of bacteremia caused by vaccine strain L. monocytogenes (Axalimogene filolisbac) occurring 31 months after immunization against human papilloma virus (HPV) associated cervical cancer. Conclusion: Receipt of a L. monocytogenes-based vaccine is a novel risk factor for delayed L. monocytogenes bacteremia. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03008126
Volume :
47
Issue :
3
Database :
Complementary Index
Journal :
Infection
Publication Type :
Academic Journal
Accession number :
136714636
Full Text :
https://doi.org/10.1007/s15010-018-1249-7