Pinning Controllers for Activation Output Tracking of Boolean Network Under One-Bit Perturbation.

This paper studies pinning controllers for activation output tracking (AOT) of Boolean network under one-bit perturbation, based on the semitensor product of matrices. First, the definition of AOT with respect to an activation number is presented, where the activation number means the number of active outputs whose logical variables are 1 s. Then, several criteria are established for AOT issue. Further, the impact of one-bit perturbation on AOT is studied, where one-bit perturbation means that only one logical function has one-bit change of its truth table by flipping the value from 1 to 0 or 0 to 1. In addition, if a one-bit perturbation is a valid perturbation on AOT, an output feedback pinning control is designed to recover AOT. The obtained results are effectively illustrated by a D. melanogaster segmentation polarity gene network and a reduced signal transduction network. [ABSTRACT FROM AUTHOR]