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Ibrutinib enhances the efficacy of ROR1 bispecific T cell engager mediated cytotoxicity in chronic lymphocytic leukaemia.
- Source :
- British Journal of Haematology; Jul2019, Vol. 186 Issue 2, p380-382, 3p, 2 Graphs
- Publication Year :
- 2019
-
Abstract
- The article discusses the ibrutinib enhances the efficacy of ROR1 bispecific T cell engager mediated cytotoxicity in chronic lymphocytic leukaemia. Topics include how receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an onco-fetal antigen expressed in a range of solid and haematological malignancies, including acute lymphoblastic leukaemia (ALL) and chronic lymphocytic leukaemia.
- Subjects :
- T cells
T cell receptors
PERFORINS
B cells
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 186
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 137267060
- Full Text :
- https://doi.org/10.1111/bjh.15911