Preface for the Special Issue on Dynamical Models of Biology and Medicine.

Highlights from the article: Areas covered include general mathematical methods and their applications in biology and medicine, with an emphasis on work related to mathematical and computational modeling of the complex dynamics observed in biological and medical research. They proposed and validated a novel type of mathematical model of androgen resistance development in prostate cancer patients under intermittent androgen suppression therapy. While authors of these papers deal with very different modeling questions, they are all well motivated by specific applications in biology and medicine and employ innovative mathematical and computational methods to study their complex model dynamics. 13 Baez J., Kuang Y. Mathematical Models of Androgen Resistance in Prostate Cancer Patients under Intermittent Androgen Suppression Therapy.