Combined orthodontic and surgical treatment in PTH1R‐negative 'primary failure of eruption'‐like anomalies: report of two cases with satisfactory long‐term response to traction.

Introduction: Primary failure of eruption (PFE) is a sporadic or inherited disorder of dental eruption that can be caused by mutations in the PTH1R gene. PFE typically manifests as a severe posterior open bite. Orthodontic treatment is considered ineffective in PFE. Case presentation: Here, we report two unrelated PTH1R‐negative cases of severe eruption disorders presenting several of the typical clinical features of PFE, and where we tracted the impacted teeth using Bollard bone anchors. Management: We managed to obtain a satisfactory occlusion in both cases without extended ankylosis induced by the orthodontic movements based on bone anchors. Outcome: These cases underline the need for a better understanding of the genetics of dental eruption disorders related to PFE before establishing strict clinical guidelines ruling out potentially efficient orthodontic management protocols within the PFE spectrum. [ABSTRACT FROM AUTHOR]