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ApiAP2 Transcription Factors in Apicomplexan Parasites.

Authors :
Jeninga, Myriam D.
Quinn, Jennifer E.
Petter, Michaela
Source :
Pathogens; Jun2019, Vol. 8 Issue 2, p47, 1p
Publication Year :
2019

Abstract

Apicomplexan parasites are protozoan organisms that are characterised by complex life cycles and they include medically important species, such as the malaria parasite Plasmodium and the causative agents of toxoplasmosis (Toxoplasma gondii) and cryptosporidiosis (Cryptosporidium spp.). Apicomplexan parasites can infect one or more hosts, in which they differentiate into several morphologically and metabolically distinct life cycle stages. These developmental transitions rely on changes in gene expression. In the last few years, the important roles of different members of the ApiAP2 transcription factor family in regulating life cycle transitions and other aspects of parasite biology have become apparent. Here, we review recent progress in our understanding of the different members of the ApiAP2 transcription factor family in apicomplexan parasites. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20760817
Volume :
8
Issue :
2
Database :
Complementary Index
Journal :
Pathogens
Publication Type :
Academic Journal
Accession number :
137458611
Full Text :
https://doi.org/10.3390/pathogens8020047