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Impact of blood pressure levels within first 24 hours after mechanical thrombectomy on clinical outcome in acute ischemic stroke patients.
Impact of blood pressure levels within first 24 hours after mechanical thrombectomy on clinical outcome in acute ischemic stroke patients.
- Source :
- Journal of NeuroInterventional Surgery; Aug2019, Vol. 11 Issue 8, p735-739, 5p, 6 Charts
- Publication Year :
- 2019
-
Abstract
- Introduction Despite early management and technical success of mechanical thrombectomy (MT) for acute ischemic stroke (AIS), not all patients reach a good clinical outcome. Different factors may have an impact and we aimed to evaluate blood pressure (BP) levels in the first 24 hours after MT. Methods consecutive AIS patients treated with MT were enrolled in the retrospective bi-center study. Neurological deficit was assessed with National Institutes of Health Stroke Scale (NIHSS) and functional outcome after 3 months with modified Rankin scale (mRS) with a score 0-2 for good outcome. The presence of symptomatic intracerebral hemorrhage (SICH) was assessed according to the SITS-MOST criteria. results Of 703 treated patients, completed BP levels were collected in 690 patients (350 males, mean age 71±13 years) with median of admission NIHSS 17 points. Patients with mRS 0-2 had a lower median of systolic BP (SBP) compared with those with poor outcome (131 vs 140 mm Hg, P<0.0001). The rate of SICH did not differ between the patients with a median of SBP <140 mm Hg and ≥140 mm Hg. (5.1% vs 5.1%, P=0.980). Multivariate regression analysis with adjustment for potential confounders showed a median of distolic BP (P=0.024, OR: 0.977, 95% CI: 0.957 to 0.997) as a predictor of good functional outcome after MT, and a median of maximal SBP (P=0.038; OR: 0.990, 95% CI: 0.981 to 0.999) in the patients with achieved recanalization. Conclusion Lowering of BP within the first 24 hours after MT may have a positive impact on clinical outcome in treated patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- STROKE diagnosis
BLOOD pressure
BLOOD pressure measurement
CEREBRAL hemorrhage
CEREBRAL ischemia
MULTIVARIATE analysis
POSTOPERATIVE period
STROKE
THROMBOSIS
VEIN surgery
MULTIPLE regression analysis
TREATMENT effectiveness
RETROSPECTIVE studies
ACUTE diseases
CONFOUNDING variables
NIH Stroke Scale
Subjects
Details
- Language :
- English
- ISSN :
- 17598478
- Volume :
- 11
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Journal of NeuroInterventional Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 137650629
- Full Text :
- https://doi.org/10.1136/neurintsurg-2018-014548