The presence of virus significantly associates with chronic rhinosinusitis disease severity.

We aimed to investigate the sinonasal virome of patients with CRS in relation to disease phenotype, to compare it to healthy controls, and to explore any association between more severe disease and viral presence. GLO:1X5/01aug19:all13772-fig-0002.jpg PHOTO (COLOR): Objective (top) and subjective (bottom) disease scores in virus-negative and virus-positive patients. It is the first study to demonstrate their significant association with more severe radiological and endoscopic disease in I virus-positive i CRSsNP patients but not I virus-positive i patients with CRSwNP. [Extracted from the article]