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Effector gene reshuffling involves dispensable mini-chromosomes in the wheat blast fungus.
- Source :
- PLoS Genetics; 9/12/2019, Vol. 15 Issue 9, p1-23, 23p
- Publication Year :
- 2019
-
Abstract
- Newly emerged wheat blast disease is a serious threat to global wheat production. Wheat blast is caused by a distinct, exceptionally diverse lineage of the fungus causing rice blast disease. Through sequencing a recent field isolate, we report a reference genome that includes seven core chromosomes and mini-chromosome sequences that harbor effector genes normally found on ends of core chromosomes in other strains. No mini-chromosomes were observed in an early field strain, and at least two from another isolate each contain different effector genes and core chromosome end sequences. The mini-chromosome is enriched in transposons occurring most frequently at core chromosome ends. Additionally, transposons in mini-chromosomes lack the characteristic signature for inactivation by repeat-induced point (RIP) mutation genome defenses. Our results, collectively, indicate that dispensable mini-chromosomes and core chromosomes undergo divergent evolutionary trajectories, and mini-chromosomes and core chromosome ends are coupled as a mobile, fast-evolving effector compartment in the wheat pathogen genome. [ABSTRACT FROM AUTHOR]
- Subjects :
- RICE blast disease
WHEAT
MOBILE genetic elements
BOTANY
FUNGAL genetics
Subjects
Details
- Language :
- English
- ISSN :
- 15537390
- Volume :
- 15
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- PLoS Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 138581845
- Full Text :
- https://doi.org/10.1371/journal.pgen.1008272