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2H-Pyranone and isocoumarin derivatives isolated from the plant pathogenic fungus Leptosphaena maculans.
- Source :
- Journal of Asian Natural Products Research; Oct2019, Vol. 21 Issue 10, p939-946, 8p
- Publication Year :
- 2019
-
Abstract
- Two new 2H-pyranones and two new isocoumarin derivatives, maculanslines A-D (1–4), together with seven known compounds (5–11), were isolated from the plant pathogenic fungus Leptosphaena maculans. Their planar structures and absolute configuration were elucidated by comprehensive spectroscopic techniques including high-resolution electrospray ionization mass spectrum, 1D and 2D nuclear magnetic resonance, as well as electronic circular dichroism. All 11 compounds were tested for their inhibitory activity against α-glucosidase. Compound 1 showed moderate inhibitory activity against α-glucosidase with IC<subscript>50</subscript> of 74.35 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 21
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 138615528
- Full Text :
- https://doi.org/10.1080/10286020.2018.1485661