Back to Search
Start Over
Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data.
- Source :
- Annals of the Rheumatic Diseases; Jul2018, Vol. 77 Issue 7, p1017-1024, 8p, 1 Diagram, 4 Charts
- Publication Year :
- 2018
-
Abstract
- <bold>Objectives: </bold>The aim of this study was to assess the psychological well-being and to analyse factors associated with depressive symptoms in axial spondyloarthritis (axSpA).<bold>Methods: </bold>A stratified random sample of subjects with a diagnosis of axSpA (International Classification of Diseases, Tenth Revision, German Modification M45) was drawn from health insurance data in Germany. These persons received a postal questionnaire on disease-related, psychological and lifestyle factors as well as socioeconomic status. Additional information to verify the axSpA diagnosis was also collected. The psychological well-being was assessed by means of the 5-item WHO Well-Being Index (WHO-5), which is considered a screening tool for depression. The following established cut-offs on the WHO-5 were applied: >50: good well-being, no depressive symptoms; 29-50: mild depressive symptoms; ≤28: moderate-to-severe depressive symptoms. Information on comorbidities, drug prescriptions and non-pharmacological treatment was retrieved from claims data and linked to the questionnaire data.<bold>Results: </bold>A total of 1736 persons with a confirmed axSpA diagnosis were included. Using the cut-offs on the WHO-5, 533 persons (31%) were found to have moderate-to-severe depressive symptoms, 479 (28%) had mild depressive symptoms and 724 (42%) had a good well-being. Multivariable logistic regression revealed that higher disease activity, higher level of functional impairment, lower income, self-reported stress and lack of exercise, and younger age represent factors associated with moderate-to-severe depressive symptoms.<bold>Conclusions: </bold>The prevalence of depressive symptoms in axSpA subjects is high and associated with disease-related parameters, socioeconomic status and lifestyle factors. These findings highlight the need for the careful evaluation of depressive symptoms as a part of the management strategy for axSpA. [ABSTRACT FROM AUTHOR]
- Subjects :
- AGE distribution
ANKYLOSING spondylitis
COMPARATIVE studies
MENTAL depression
DISABILITY evaluation
LONGITUDINAL method
RESEARCH methodology
MEDICAL cooperation
MULTIVARIATE analysis
PROGNOSIS
QUALITY of life
RESEARCH
RISK assessment
SACROILIAC joint
SEX distribution
SICKNESS Impact Profile
SPONDYLOARTHROPATHIES
LOGISTIC regression analysis
EVALUATION research
SEVERITY of illness index
Subjects
Details
- Language :
- English
- ISSN :
- 00034967
- Volume :
- 77
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Annals of the Rheumatic Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 138971185
- Full Text :
- https://doi.org/10.1136/annrheumdis-2017-212629